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Look at alternant therapies that are not reasonable CYP3A inducers for the duration of treatment with mitapivat. If struggling to avoid coadministration, check Hb and titrate further than fifty mg BID, if vital, but do not exceed mitapivat dose of one hundred mg BID. .Observe Closely (1)pentobarbital will raise the stage or effect of clopidogrel by

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